Treatment Options For Patients With Severe Bilateral Corneal Blindness
Auro Kpro is a low-cost, artificial cornea (keratoprosthesis) used to treat end-stage corneal blindness, especially in cases where a traditional corneal transplant is likely to fail. Manufactured by Aurolab in India, it is designed as a more affordable alternative to the Boston Kpro, particularly for use in developing countries. How it worksThe Auro Kpro is a Type 1 keratoprosthesis, which means it is used in eyes with a relatively normal ocular surface and eyelid function. The device is comprised of three parts:
Front plate with a central optical stem: This creates the optical pathway for vision.
Backplate: Made of PMMA, unlike the Boston Kpro, which uses titanium.
Locking ring: This part secures the device.
For the implant, a standard donor corneal graft is prepared, and the Auro Kpro is securely assembled and placed within it. The entire assembly is then surgically implanted into the patient's eye. Intended useAuro Kpro is considered a primary treatment option for patients with severe corneal opacity where standard donor corneal transplants are unlikely to succeed. These conditions include:
Multiple failed corneal grafts: When previous corneal transplants have failed.
Severe chemical injuries: Damage to the cornea from chemical burns.
Extensive corneal vascularization: When the cornea is flooded with blood vessels, which increases the risk of graft rejection.Benefits and considerations
Benefits
Effectiveness: Studies show that Auro Kpro has comparable visual outcomes, retention rates, and complication rates to the more expensive Boston Kpro.
Cost-effectiveness: As a low-cost alternative, it greatly increases the accessibility of keratoprosthesis surgery in low- and middle-income countries.
Salvages vision: It provides a viable option for salvaging and restoring vision in patients with end-stage corneal disease. Potential complications and risks
Retroprosthetic membrane (RPM): A membrane can form behind the implant, which is a common and potentially serious complication.
Glaucoma: Patients face a risk of developing or progressing glaucoma after implantation.
Extrusion and breakage: Complications like the device pushing out (extrusion) or breaking are possible, though less common.
Lifelong follow-up: Patients require long-term follow-up and management of potential complications.
Infection risk: Long-term topical antibiotic drops are required to minimize the risk of infection.
